Histologic effects of intentional-socket-assisted orthodontic movement in rabbits
유지연, 이원, 박재현, Bayome Mohamed, 국윤아, 김용,
소속 상세정보
유지연 ( Yu Ji-Yeon ) - Catholic University Graduate School of Medicine
이원 ( Lee Won ) - Catholic University Uijeongbu St. Mary’s Hospital Department of Oral and Maxillofacial Surgery
박재현 ( Park Jae-Hyun ) - A.T. Still University Arizona School of Dentistry & Oral Health
( Bayome Mohamed ) - Catholic University School of Medicine Department of Orthodontics
국윤아 ( Kook Yoon-Ah ) - Catholic University Seoul St. Mary’s Hospital Department of Orthodontics
김용 ( Kim Yong ) - Australia Dental Focus
KMID : 0361920120420040207
Abstract
Objective: This study aimed to evaluate the effect of an intentionally created socket on bone remodeling with orthodontic tooth movement in rabbits.
Methods: Eighteen male rabbits weighing 3.8 - 4.25 kg were used. An 8-mm deep and 2-mm wide socket was drilled in the bone 1 mm mesial to the right mandibular first premolar. The left first premolar was extracted to serve as an extraction socket. A traction force of 100 cN was applied to the right first premolar and left second premolar. Sections were obtained at the middle third of the moving tooth for both the drilled and extraction sockets and evaluated with hematoxylin and eosin staining and immunohistochemical analyses. The amount of tooth movement and tartrate-resistant acid phosphatase (TRAP)-positive cell count were compared between the 2 groups using the Mann-Whitney U test.
Results: At week 2, the distance of tooth movement was significantly higher in the intentional socket group (p < 0.05) than in the extraction socket group. The number of TRAP-positive cells decreased in week 2 but increased in week 3 (p < 0.05). However, there were no significant differences between the groups. Furthermore, results of transforming growth factor (TGF)-? staining revealed no significant differences.
Conclusions: The intentional socket group showed greater distance of tooth movement than did the extraction socket group at week 2. Osteoclast counts and results of immunohistochemical analyses suggested elevated bone remodeling in both the groups. Thus, osteotomy may be an effective modality for enhancing tooth movement in orthodontic treatment.
키워드
Intentional socket;Accelerated tooth movement;Bone remodeling
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